Enhancing anti-tumor immune responses by optimized combinations of cell-penetrating peptide based-vaccines and adjuvants

Elodie Belnoue, Wilma Di Berardino-Besson, Hubert Gaertner, Susanna Carboni, Isabelle Dunand-Sauthier, Fabrice Cerini, Else-Marit Suso-Inderberg, Sébastien Wälchli, Stéphane König, Andres M. Salazar, Oliver Hartley, Pierre-Yves Dietrich, Paul R. Walker and Madiha Derouazi.

Mol Ther doi:10.1038/mt.2016.134; accepted article preview online July 5, 2016

Cell-penetrating peptides - the Swiss Army knife of cancer vaccines
Walker PR, Belnoue E, Dietrich PY, Derouazi M.
Oncoimmunology. 2016 Mar; 5(3): e1095435

Novel Cell-Penetrating Peptide-Based Vaccine Induces Robust CD4+ and CD8+ T Cell-Mediated Antitumor Immunity
Derouazi M, Di Berardino-Besson W, Belnoue E, Hoepner S, Walther R, Benkhoucha M, Teta P, Dufour Y, Yacoub Maroun C, Salazar AM, Martinvalet D, Dietrich PY, Walker PR.
Cancer Res. 2015 Aug 1;75(15):3020-31

Synergy between CD8 T cells and Th1 or Th2 polarised CD4 T cells for adoptive immunotherapy of brain tumours
Hoepner S, Loh JM, Riccadonna C, Derouazi M, Maroun CY, Dietrich PY, Walker PR.
PLoS One. 2013 May 23;8(5):e63933

Immune infiltration of spontaneous mouse astrocytomas is dominated by immunosuppressive cells from early stages of tumor development
Tran Thang NN, Derouazi M, Philippin G, Arcidiaco S, Di Berardino-Besson W, Masson F, Hoepner S, Riccadonna C, Burkhardt K, Guha A, Dietrich PY, Walker PR.
Cancer Res. 2010 Jun 15;70(12):4829-39